Cellular and Molecular Biology Training Program

Angel is in the Biochemistry, Molecular and Structural Biology Graduate Program, and joined the CMB Training Program in 2022. 

Mentor: Dr. Guillaume Chanfreau

     The RES complex is a component of the spliceosome and it is important for the first catalytic step of RNA splicing.  I’m currently studying the effects that components of the Nonsense Mediated Decay pathway, such as Upf1p, have on the degradation of alternatively spliced RNAs that arise from mutations of the proteins that comprise the RES complex in Saccharomyces cerevisiae.