Langerman, Justin B.

Justin is a third year trainee and is in the Molecular Biology IDP. His research mentor is Dr. Stephen Smale. He received a B.S. degree in 2007 from UCLA.
Mentor: Dr. Stephen Smale
Research project:
Unmethylated CpG dinucleotides may mark the enhancers of tissue specific genes even in undifferentiated embryonic stem cells. Using IL12p40 as a model tissue specific gene, we are interested in showing that these enhancer marks are necessary for the function of the gene after differentiation, and in showing how these enhancer marks are functionally created and preserved.